LSD1-IN-32

LSD1-IN-32 (compound 11e) is a potent LSD1 inhibitor with an IC50 value of 0.99 µM. LSD1-IN-32 inhibits RANKL-induced osteoclastogenesis, bone resorption and F-actin belt formation. LSD1-IN-32 has the potential for the research of osteoporosis[1].

C36H56N2O3Si2

621.01

O=C(N1CCC(CN[C@H]2[C@H](C3=CC=CC=C3)C2)CC1)/C=C/C4=CC=C(O[Si](C)(C(C)(C)C)C)C(O[Si](C)(C(C)(C)C)C)=C4

Histone Methyltransferase

Room temperature