LSN2463359 [CAS 1401031-52-4]

LSN2463359 is positive allosteric modulator of metabotropic glutamate 5 (mGlu5) . LSN2463359 attenuates aspects of the behavioral response to administration of the competitive NMDA receptor antagonist. LSN2463359 selectively attenuates reversal learning deficits observed in the neurodevelopmental MAM E17 model[1]. LSN2463359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

[1401031-52-4]

C16H15N3O

265.31

O=C(C1=NC=C(C=C1)C#CC2=CC=NC=C2)NC(C)C

MGluR

98.49

DMSO : 125 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H302, H315, H319, H335

H302, H315, H319, H335