LT-626 [CAS 1207456-03-8]

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SKU:QM-0007224

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Product Details

Description
LT-626 is a potent PARP inhibitor with an IC50 of 1.60 nM. LT-626 inhibits cellular PAR synthesis with an EC50 of 17.9 nM and shows enhanced cytotoxicity in colorectal cancer cells harboring MRE11 mutations. LT-626 exhibits synergistic effects with Cisplatin , Oxaliplatin (HY-17371), and SN-38 (HY-13704) in colorectal cancer cells. LT-626 can be used for colorectal research[1].
CAS Number
[1207456-03-8]
Molecular Formula
C20H15F2N5O
Molecular Weight
379.37
Smiles
CN1C([C@H]2C=3C4=C(N[C@@H]2C5=CC=C(F)C=C5)C=C(F)C=C4C(=O)NN3)=NC=C1
Target
PARP
Shipping Conditions
Room temperature
Hazard Statement
H302-H315-H319-H335
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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LT-626 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.