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LU-32-176B [CAS 770688-66-9]
LU-32-176B [CAS 770688-66-9]
SKU:QM-0059491
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Product Details
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Description
LU-32-176B, a GABA transporter 1 (GAT1) selective inhibitor, is found to exert a synergistic anticonvulsant action with GAT2 transport inhibitor EF1502. LU-32-176B inhibits neurons, astrocytes and mGAT1 with the IC50 values of 2μM, 1μM, 4μM, respectively[1][2].
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CAS Number
[770688-66-9]
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Molecular Formula
C23H24F2N2O2
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Molecular Weight
398.45
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Smiles
OC1=NOC2=C1C(CCC2)NCCCC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F
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Target
GABA Receptor
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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LU-32-176B [CAS 770688-66-9]
LU-32-176B is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.