LY 190388 [CAS 105496-35-3]

LY 190388 is a penicillamine-containing enkefa peptide analog with μ receptor agonist activity. LY 190388 showed analgesic effect in inhibiting the writhing response in mice after intracerebroventricular administration. The analgesic effect of LY 190388 is not caused by its δ receptor agonist action, but by its μ receptor agonist activity. When LY 190388 is used together with the δ receptor antagonist ICI 174864, an additive analgesic effect is produced[1].

[105496-35-3]

C30H41N5O7S

615.74

CC([C@@H](NC([C@@H](NC(CNC([C@H](NC([C@@H](N)CC1=CC=C(O)C=C1)=O)C(S)(C)C)=O)=O)CC2=CC=CC=C2)=O)C(O)=O)C

Endogenous Metabolite

Room temperature