LY 223592 [CAS 103828-82-6]

LY 223592 (Compound I-a) is a Gemcitabine derivative. LY 223592 has the biological activity of highly selective inhibition of lung cancer cell proliferation (IC50 = 5.6 nM in A549 cells) and low cytotoxicity to normal cells. LY 223592 can be used for the research of cancer, such as non-small cell lung cancer (NSCLC).

[103828-82-6]

C10H11F2N5O4

303.22

FC1(F)[C@H](O)[C@@H](CO)O[C@H]1N2C3=C(C(N=C(N3)N)=O)N=C2

Drug Derivative

Room temperature