LY-2584702 (free base) [CAS 1082949-67-4]

LY-2584702 free base is a selective ATP competitive inhibitor of p70S6K with an IC50 of 4 nM. In S6K1 enzyme assay, the IC50 of LY-2584702 is 2 nM.

[1082949-67-4]

C21H19F4N7

445.42

CN1C=C(C2=CC=C(F)C(C(F)(F)F)=C2)N=C1C3CCN(C4=C5C(NN=C5)=NC=N4)CC3

Ribosomal S6 Kinase (RSK)

P70S6K

99.56

DMSO : ≥ 4.5 mg/mL

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H315-H319-H335

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501