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Lys-CoA (TFA)
Lys-CoA (TFA)
SKU:QM-0143506-01
£489.83 GBP
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Product Details
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Description
Lys-CoA TFA is a selective p300 histone acetyltransferase (HAT) inhibitor (IC50=50-500 nM) . Lys-CoA TFA displays >100-fold selectivity for p300 over PCAF (IC50=200 μM) . Lys-CoA TFA inhibits p300 HAT activity-dependent transcriptional activation[1][2].
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Molecular Formula
C33H54F3N10O21P3S
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Molecular Weight
1108.82
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Smiles
O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSCC(NCCCC[C@@H](C(N)=O)NC(C)=O)=O)=O)=O)(O)=O)(O)=O)O[C@H]1N2C=NC3=C(N)N=CN=C32.O=C(O)C(F)(F)F
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Target
Histone Acetyltransferase
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Isoform
CBP/p300
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Purity
99.42
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Lys-CoA (TFA)
Lys-CoA (TFA) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.