M-APTA [CAS 86072-47-1]

M-APTA (5'-S- (3-aminophenyl) -5'-thioadenosine) is a selective chemoprotective agent targeting methylthioadenosine phosphorylase (MTAP) . m-APTA can be converted into adenine, which is a crucial step in protecting normal cells from the toxicity of nucleobase analogues (NBA) . m-APTA is promising for research of MTAP-deficient cancers[1].

[86072-47-1]

C16H18N6O3S

374.42

NC1=CC=CC(SC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C=NC(C3=NC=N4)=C4N)O2)=C1

Phosphorylase

99.54

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years (Powder)

Blue Ice

H302, H315, H319, H335

H302, H315, H319, H335