M7 (3'Ma-Biotin) Gppp (2'OMe) ApG ammonium

M7 (3'Ma-Biotin) Gppp (2'OMe) ApG ammonium is a Biotin-labled cap analogue that can be used for mRNA synthesis. The efficiency of mRNA delivery can be determined by the detection of Biotin by flow cytometry, which can be used to track mRNA in cells and in living animals and to screen delivery lipid ratios.

C43H60N18O25P4S.xNH3

O=C1C([N+](C)=CN2[C@H]3[C@H](O)[C@H](CNC(CCCC[C@@H]4SC[C@]([C@]4([H])N5)([H])NC5=O)=O)[C@@H](COP(OP(OP(OC[C@H]6O[C@@H](N(C=N7)C8=C7C(N)=NC=N8)[C@H](OC)[C@@H]6OP(OC[C@H]9O[C@@H](N(C=N%10)C%11=C%10C(NC(N)=N%11)=O)[C@H](O)[C@@H]9O)([O-])=O)(O)=O)(O)=O)(O)=O)O3)=C2N=C(N)N1.N.[x]

DNA/RNA Synthesis

25 mM * 100 μL in Water

90

10 mM in H2O

Solution, -20°C, 2 years

Blue Ice