MAGL-IN-4 [CAS 2135785-20-3]

MAGL-IN-4 is an orally active, selective and reversible monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 6.2 nM. MAGL-IN-4 can penetrate the blood-brain barrier (BBB) . MAGL-IN-4 enhances endocannabinoid signaling mostly by the increase in the level of 2-AG via selective MAGL inhibition in the brain[1].

[2135785-20-3]

C18H21ClN2O4

364.82

CC1=C(C=C(C=C1)COC2CN(C([C@H]3C[C@]4(COC(N4)=O)C3)=O)C2)Cl

MAGL

99.79

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature