MAO-B-IN-24

MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B (IC50: 1.60 μM) . MAO-B-IN-24 also inhibited MAO-A (22.42 μM) ; at 10 μM concentration, it also reduced AChE and BChE activities to 54.58% and 88.43%[1].

C20H18N2O

302.37

O=C1C2(CCCC2)N(CC3=CC=C(C#N)C=C3)C4=CC=CC=C41

Cholinesterase (ChE) ; Monoamine Oxidase

10 mM in DMSO

Room temperature