MAO-B-IN-39 [CAS 3094045-97-0]

MAO-B-IN-39 (compound11) is a selective monoamine oxidase B (MAO-B) inhibitor. MAO-B-IN-39 inhibits MAO-Bwith an IC50 of 3.61 μM. MAO-B-IN-39 demonstrates a potent NRF2 induction capacity. MAO-B-IN-39 exhibits potent anti-inflammatory and neuroprotective activity in OS (oxidative stress) -related in vitro models. MAO-B-IN-39 demonstrates high liver microsomal stability and favorable pharmacokinetics in mice. MAO-B-IN-39 is potential for Parkinson’s disease (PD) research[1].

[3094045-97-0]

C17H13FN2O

280.3

O=C(NC1=CC=C2NC=CC2=C1)/C=C/C3=C(C=CC=C3)F

Keap1-Nrf2; Monoamine Oxidase

MAO-A; MAO-B

Room temperature