MAO-B-IN-44 [CAS 1454707-25-5]

MAO-B-IN-44 (Compound 4n) is a selective monoamine oxidase B (MAO-B) inhibitor targetin with an IC50 value of 1.01 μM, showing weak inhibition on MAO-A (IC50=14.4 μM) . MAO-B-IN-44 reduces degradation of neurotransmitters like dopamine. MAO-B-IN-44 is promising for research of neurodegenerative diseases related to MAO-B abnormalities such as Parkinson’s disease[1].

[1454707-25-5]

C34H32N4O8

624.64

O=C(C1=C(NC2=CC=C(OC)C=C2)CC(C3=CC=C([N+]([O-])=O)C=C3)N(C4=CC=C(OC)C=C4)C1C5=CC=C([N+]([O-])=O)C=C5)OCC

Monoamine Oxidase

MAO-A; MAO-B

Room temperature