MAP4K4-IN-3 (Compound 17) is a potent and selective MAP4K4 inhibitor with an IC50 of 14.9 nM in kinase assay, an IC50 of 470 nM in cell assay. Antidiabetic agent[1].
CAS Number
[1811510-58-3]
Molecular Formula
C15H12ClN5
Molecular Weight
297.74
Smiles
NC1=NC=C(C2=CC(C3=CC=C(Cl)C=C3)=C(N)N=C2)C=N1
Target
MAP4K
Isoform
MAP4K4/HGK
Purity
99.15
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)