MAT2A-IN-2 [CAS 2565671-21-6]

MAT2A-IN-2 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally high in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-2 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-2 has the potential for the research of cancer diseases (extracted from patent WO2020243376A1, compound 172) [1].

[2565671-21-6]

C23H17F3N6O2

466.42

O=C1C(C2=CN3C=CN=C3C=C2)=CC4=C(N1C5=CC=C(C=C5)OC)N=C(NCC(F)(F)F)N=C4

Somatostatin Receptor

10 mM in DMSO

Room temperature