Mavacamten-d1 [CAS 2453251-02-8]

Mavacamten-d1 (MYK461-d1; SAR439152-d1) is deuterium labeled Mavacamten. Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.

[2453251-02-8]

C15H18DN3O2

274.34

CC(N(C1=O)C(C=C(N[C@H](C2=CC=C([2H])C=C2)C)N1)=O)C

Isotope-Labeled Compounds; Myosin

10 mM in DMSO

Room temperature