Mavacamten-d6 [CAS 2453251-18-6]

Mavacamten-d6 (MYK461-d6; SAR439152-d6) is deuterium labeled Mavacamten. Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.

[2453251-18-6]

C15H13D6N3O2

279.37

[2H]C([2H])([2H])C(N1C(C=C(NC1=O)N[C@H](C2=CC=CC=C2)C)=O)C([2H])([2H])[2H]

Isotope-Labeled Compounds; Myosin

10 mM in DMSO

Room temperature