MC1

MC1 is a potent NLRP3 inhibitor with a KD value of 19.3 nM. MC1 shows no cytotoxicity. MC1 ameliorates cognitive deficits without eliciting adverse effects and shows an absence of hepatotoxicity. MC1 has the potential for the research of Alzheimer's disease (AD) [1].

C23H23N3O6S2

501.58

O=C(NS(C1=CC(C(C)(O)C)=CS1)(=O)=O)NC2=C(C3=CC=C([N+]([O-])=O)C=C3)C=CC4=C2CCC4

NOD-like Receptor (NLR)

NLRP3

Room temperature