MC12

MC12 is a thiazole-based derivative and a SARS-CoV-2 main protease inhibitor (IC50: 77.7 nM) . MC12 exhibits inhibitory effects on both SARS-CoV and SARS-CoV-2 main proteases, with low cytotoxicity and good stability. MC12 can be used in the research of anti-COVID-19 drugs[1].

C16H12ClN3O2S

345.8

ClC1=CN=CC(OC(C2=CSC(N(C)C3=CC=CC=C3)=N2)=O)=C1

SARS-CoV; Virus Protease

Room temperature