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MCaE12A

MCaE12A

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SKU:QM-0092751

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  • Description

    MCaE12A is a high-affinity modulator of RyR2 and increases RyR2 sensitivity to cytoplasmic calcium concentrations promoting channel opening. MCaE12A acts as an important tool for RyR2 structure-to-function studies as well as for manipulating Ca2+ homeostasis and dynamic of cardiac cell[1].

  • Molecular Formula

    C154H268N56O44S6

  • Molecular Weight

    3800.51

  • Smiles

    O=C(N[C@@H](CC(O)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@H]1CCCCN)=O)=O)=O)NC2=O)C(N[C@@H](CC(C)C)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@H]5CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC1=O)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@H]2CSSC[C@@H](C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)NC5=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN

  • Target

    Calcium Channel

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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MCaE12A

MCaE12A is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.