MCG-02

MCG-02 is the inhibitor for cruzain (CRZ) and cathepsin L-like protease (CATL), that inhibits the CRZ in Trypanosoma cruzi and CATL in Trypanosoma brucei with the IC50 0.2 μM and 0.02 μM[1].

C13H13N3O2S

275.33

CC1=CC=C2C(OC(C(/C(C)=N/NC(N)=S)=C2)=O)=C1

Parasite

Room temperature