Mcl1-IN-11 [CAS 2042211-13-0]

Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively[1].

[2042211-13-0]

C38H41N3O5S2

683.88

CC1(C)C2=CC(C)=C(C(C3=CC=C(C(NS(=O)(C4=CC=C(NCCSC5=CC=CC=C5)C([N+]([O-])=O)=C4)=O)=O)C=C3)=C)C=C2C(C)(C)CC1

Bcl-2 Family

10 mM in DMSO

Room temperature