Mcl1-IN-9 [CAS 1810769-31-3]

Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM[1].

[1810769-31-3]

C37H39ClN4O4

639.18

O=C1C2=C(CCCOC3=CC(C)=C(Cl)C(C)=C3)C4=CC=CC(C5=C(C)N(C)N=C5C)=C4N2CCCN1CC6=CC=CC(C(O)=O)=C6

Bcl-2 Family

Mcl-1

10 mM in DMSO

Room temperature