(-) -MDO-NPA [CAS 81264-57-5]

(-) -MDO-NPA is an N-propylnorapomorphine analog and a D1R/D2R dual-target ligand. (-) -MDO-NPA has EC50 values of 1949 nM (D1R) and 520 nM (D2R) for β-arrestin. (-) -MDO-NPA has EC50 values of 717.5 nM (D1R) and 7.7 nM (D2R) for cAMP. (-) -MDO-NPA can be used in the research of dopamine-related diseases such as Parkinson’s disease[1].

[81264-57-5]

C20H21NO2

307.39

CCCN1[C@@]2([H])C3=C(CC1)C=CC=C3C4=C(C2)C=CC5=C4OCO5

Dopamine Receptor

Room temperature