MDVN1003 [CAS 2058116-52-0]

MDVN1003 is a Bruton's tyrosine kinase (BTK) and phosphatidylinositol-3-kinase delta (PI3Kδ) dual inhibitor which prevents the activation of B cells and inhibits the phosphorylation of protein kinase B (AKT) and extracellular signal-regulated kinase 1/2 (ERK 1/2) . MDVN1003 can be used for non-Hodgkin’s lymphoma (NHL) research[1].

[2058116-52-0]

C22H20FN7O

417.44

NC1=C2C(N(C3CC(C=CC(N)=C4)=C4C3)N=C2C5=CC(NCCO6)=C6C(F)=C5)=NC=N1

PI3K

Room temperature