MEG (hemisulfate) [CAS 3979-00-8]
MEG (hemisulfate) [CAS 3979-00-8]
SKU:QM-0063415
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Product Details
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Description
MEG (Mercaptoethylguanidine) hemisulfate is a potent and selective inhibitor of the inducible NO synthase (iNOS), with EC50s of 11.5, 110, and 60 μM for iNOS, ecNOS, and bNOS respectively in tissue homogenates. MEG hemisulfate is also a potent scavenger of peroxynitrite and inhibits peroxynitrite-induced oxidative processes. MEG hemisulfate has a protective effect in many experimental models of inflammation, including ischemia/reperfusion injury, periodontitis, hemorrhagic shock, inflammatory bowel disease, and endotoxic and septic shock[1][2][3][4].
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CAS Number
[3979-00-8]
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Molecular Formula
C3H9N3S.1/2H2O4S
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Molecular Weight
168.23
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Smiles
NC(NCCS)=N.O=S(O)(O)=O.[1/2]
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Target
NO Synthase
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Isoform
INOS
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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MEG (hemisulfate) [CAS 3979-00-8]
MEG (hemisulfate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.