Melatonin [CAS 73-31-4]

Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4]. Melatonin attenuates palmitic acid-induced mouse granulosa cells apoptosis via endoplasmic reticulum stress[5].

[73-31-4]

C13H16N2O2

232.28

CC(NCCC1=CNC2=C1C=C(OC)C=C2)=O

Apoptosis; Autophagy; Endogenous Metabolite; Melatonin Receptor; Mitophagy

Human Endogenous Metabolite; Microbial Metabolite

99.98

DMSO : 100 mg/mL (ultrasonic) |Ethanol : 12.5 mg/mL (ultrasonic) |H2O : 1.1 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H302, H315, H319, H335

H302, H315, H319, H335