Melengestrol acetate-d2

Melengestrol acetate-d2 is the deuterium labeled Melengestrol acetate. Melengestrol acetate is a progesterone derivative, acts as an orally active corticosteroid hormone to promote endometrial proliferation, pregnancy maintenance, and delay of menstrual activity[1]. Melengestrol Acetate is used as a contraceptive agent for growth promoting effects and suppression of estrus in animals. Melengestrol acetate inhibits both the androgen-dependent and -independent prostatic tumors in vivo and can be used for cancer research[2].

C25H30D2O4

398.53

CC([C@@]1(OC(C)=O)C(C[C@@]2([H])[C@]3([H])C=C(C)C4=CC(C([2H])([2H])C[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=C)=O

Isotope-Labeled Compounds; Progesterone Receptor

10 mM in DMSO

Room temperature