MELK-8a [CAS 1922153-17-0]

Name: MELK-8a [CAS 1922153-17-0]
Brand: QuantiMol
SKU: QM-0079248-01
Price: 414.5 GBP
Availability: InStock

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SKU:QM-0079248-01

£414.50 GBP

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Product Details

Description
MELK-8a (NVS-MELK8a) is a highly potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor with IC50 of 2 nM. MELK-8a also inhibits Flt3 (ITD), Haspin, PDGFRα with IC50s of 0.18, 0.19, and 0.42 μM, respectively. MELK plays an essential role in regulating cell mitosis in a subset of cancer cells[1].
CAS Number
[1922153-17-0]
Molecular Formula
C25H32N6O
Molecular Weight
432.56
Smiles
CN(CC1)CCN1C2=CC=C(N3C=C(C4=CC=NC=C4OCC5CCNCC5)C=N3)C=C2
Target
Haspin Kinase; MELK; Mitosis; PDGFR
Purity
98.32
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
25 mgQM-0079248-01	25 mgQM-0079248-01 £414.50/ea	£0.00	Quantity	£414.50/ea	£0.00

50 mgQM-0079248-02	50 mgQM-0079248-02 £602.83/ea	£0.00	Quantity	£602.83/ea	£0.00

100 mgQM-0079248-03	100 mgQM-0079248-03 £878.63/ea	£0.00	Quantity	£878.63/ea	£0.00

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MELK-8a is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.