MEN-91507 [CAS 197506-04-0]

MEN-91507 is an orally activecysteinyl leukotriene receptor 1 (CysLTR1) receptor antagonist. MEN-91507 behaves as insurmountable antagonist of Leukotriene D4 -induced calcium transients, with a pKb of 10.25. MEN-91507 can inhibit Leukotriene D4-induced bronchoconstriction and microvascular leakage in guinea-pigs. MEN-91507 can be used for the researches of inflammation, immunology[1].

[197506-04-0]

C28H23FN4O3

482.51

O=C1C=C(C2=NN=NN2)OC3=C(/C=C/C4=CC=C(OCCCCC5=CC=C(F)C=C5)C=C4)C=CC=C13

Leukotriene Receptor

LTD4/CysLT1

Room temperature