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MET/PDGFRA-IN-2
MET/PDGFRA-IN-2
SKU:QM-0068416
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Product Details
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Description
MET/PDGFRA-IN-2 (compound 8h) is a MET and PDGFRA protein inhibitor. MET/PDGFRA-IN-2 induces cell apoptosis. MET/PDGFRA-IN-2 inhibits proliferation of MET-positive cells (IC50s: 9.7, 6.1, 12.0, 11.5, 8.6, 34.4 μM for AsPc-1, EBC-1, MKN-45, Mia-Paca-2, HT-29, K562 cells respectively) [1].
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Molecular Formula
C29H29N7O
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Molecular Weight
491.59
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Smiles
CC(C1=CC=C(C=C1)CN2N=NC(COC3=CC=C(C=C3)/C=N/NC4=C5C=CC=CC5=NC=N4)=C2)(C)C
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Target
Apoptosis; c-Met/HGFR; PDGFR
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Isoform
PDGFRα
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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MET/PDGFRA-IN-2
MET/PDGFRA-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.