Metallo-β-lactamase-IN-8 [CAS 1610537-25-1]

Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs), with IC50s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1, ImiS, IMP-1 and VIM-2, respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity[1].

[1610537-25-1]

C13H11ClN2O4S

326.76

O=C(NO)C1=CC=C(NS(=O)(C2=CC=C(Cl)C=C2)=O)C=C1

Bacterial; Beta-lactamase

10 mM in DMSO

Room temperature