Methyl salvionolate A [CAS 1015171-69-3]

Methyl salvionolate A is a potent inhibitor of HIV-1. Methyl salvionolate A inhibits P24 antigen in HIV-1 infected MT-4 cell with an EC50 of 1.62 μg/ml. Methyl salvionolate A also inhibits HIV-1 reverse transcriptase, protease and integrase with IC50s of 50.58, 10.73 and 7.58 μg/ml, respectively[1].

[1015171-69-3]

C27H24O10

508.47

OC(C=C1/C=C/C2=C(C=CC(O)=C2O)/C=C/C(O[C@@H](C(OC)=O)CC3=CC(O)=C(C=C3)O)=O)=C(C=C1)O

HIV

10 mM in DMSO

Room temperature