MEY-003 [CAS 3047891-88-0]

MEY-003 is an Autotaxin (ATX) inhibitor with EC50s of 460 nM and 1.09 μM for hATX-β and hATX-ɣ (analysis with LPC18:1) . MEY-003 behaves as a non-competitive inhibitor with K iof 432 nM. MEY-003 can be used for targeted ATX-related disease research [1].

[3047891-88-0]

C22H21NO4

363.41

OC1=C2C(OC(C3=CN(CCCCC)C4=C3C=CC=C4)=CC2=O)=CC(O)=C1

Phosphodiesterase (PDE)

Autotaxin

10 mM in DMSO

Room temperature