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SKU:QM-0155260-01
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MI-136 is an inhibitor of the menin-MLL protein-protein interaction (PPI), with an IC50 of 31 nM and a Kd of 23.6 nM. MI-136 shows to block AR signaling and has the potential for the study in castration-resistant tumors[1][2].
[1628316-74-4]
C23H21F3N6S
470.51
FC(F)(F)CC(S1)=CC2=C1N=CN=C2NC3CCN(CC4=CC=C(NC(C#N)=C5)C5=C4)CC3
Androgen Receptor; Apoptosis; Epigenetic Reader Domain
99.04
DMSO : 110 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302, H315, H319, H335
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MI-136 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.