Miaosporone A

Miaosporone A, an angucyclic quinone, exhibits antimalarial activity against Plasmodium falciparum K1 and antibacterial activity against Mycobacterium tuberculosis with respective IC50 values of 2.5 and 2.4 μM and displays cytotoxic activities against both cancerous (MCF-7 and NCI-H187) and nonmalignant (Vero) cells[1].

C19H18O5

326.34

O[C@]12CCC(C(C3=C(C4=O)C=CC=C3O)=O)=C4[C@@]1([H])[C@H](O)C=C(C)C2

Endogenous Metabolite; Parasite

Microbial Metabolite; Plasmodium

10 mM in DMSO

Room temperature