Microcolin H [CAS 2408008-21-7]

Microcolin H is a marine lipopeptide and phosphatidylinositol transfer protein ligand that targets PITPα/β. Microcolin H increases the conversion of LC3I to LC3II and reduces p62 levels in cancer cells, leading to autophagy cell death (Autophagy) . Microcolin H effectively inhibits tumor development and has anti-proliferative activity in nude mouse subcutaneous tumor models[1].

[2408008-21-7]

C38H63N5O9

733.93

O=C(N1[C@H](C=CC1=O)C)[C@H]2N(C[C@H](C2)O)C([C@H](C(C)C)N(C)C([C@H]([C@@H](C)OC(C)=O)NC([C@H](CC(C)C)N(C)C([C@H](C)CCCCCC)=O)=O)=O)=O

Atg8/LC3; Autophagy; p62

99.13

DMSO : 50 mg/mL (ultrasonic)

-80°C, 2 years; -20°C, 1 year (Powder, stored under nitrogen, away from moisture)

Blue Ice