Miglitol [CAS 72432-03-2]

Miglitol (BAY-m1099) is an orally active antidiabetic compound that inhibits the breakdown of glycoconjugates into glucose. Miglitol inhibits glycoside hydrolase enzymes called α-glucosidases. Miglitol inhibits oxidative stress-induced apoptosis and mitochondrial ROS over-production in endothelial cells by enhancement of AMP-activated protein kinase. Dietary supplementation with Miglitol from pre-onset stage in OLETF rats delays the onset and development of diabetes and preserves the insulin secretory function of pancreatic islets[1][2][3][4].

[72432-03-2]

C8H17NO5

207.22

O[C@@H]1[C@@H](CO)N(CCO)C[C@H](O)[C@H]1O

AMPK; Glycosidase; Reactive Oxygen Species (ROS)

98

H2O : ≥ 200 mg/mL

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H315, H319

H315, H319