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SKU:QM-0140282-01
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MIND4-17 is a potent NRF2 activator that covalently modifies a C151 residue of Keap1. MIND4-17 disrupts Keap1-Nrf2 association, leading to Nrf2 protein stabilization and nuclear translocation. MIND4‐17 exerts potent antioxidant activity[1][2].
[345989-24-4]
C20H15N5O3S
405.43
O=[N+](C1=CN=C(C=C1)SC2=NN=C(COC3=CC=CC=C3)N2C4=CC=CC=C4)[O-]
Keap1-Nrf2
99.93
DMSO : 100 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H315, H319, H335
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MIND4-17 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.