Mitraphylline [CAS 509-80-8]

Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils. Mitraphylline exhibits antiproliferative activity in human glioma and neuroblastoma cell lines. Mitraphylline can inhibit interleukin release in vivo[1][2][3].

[509-80-8]

C21H24N2O4

368.43

O=C1NC2=C([C@@]13CCN4C[C@@]5([C@@H](OC=C([C@]5(C[C@]43[H])[H])C(OC)=O)C)[H])C=CC=C2

Interleukin Related; NF-κB

99.3

DMSO : 6.76 mg/mL (ultrasonic)

4°C (Powder, sealed storage, away from moisture and light)

Room Temperature

H300

H300