Mizacorat [CAS 1893415-00-3]

Mizacorat (AZD9567; compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1].

[1893415-00-3]

C27H28F2N4O3

494.53

CC(F)(F)C(N[C@H]([C@H](OC1=CC2=C(N(C(C=C3)=CN(C)C3=O)N=C2)C=C1)C4=CC=CC=C4)C(C)C)=O

Glucocorticoid Receptor

10mM

99.34

DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature