Mizagliflozin [CAS 666843-10-3]

Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic agent that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation[1].

[666843-10-3]

C28H44N4O8

564.67

O=C(N)C(C)(C)CNCCCOC1=CC=C(CC2=C(C(C)C)NN=C2O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C(C)=C1

SGLT

SGLT1

99.2

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

4°C (Powder, protect from light)

Room Temperature