MK-2748 [CAS 1193902-95-2]

MK-2748 is a hepatitis C virus (HCV) NS3/4a protease inhibitor. MK-2748 exhibits broad-spectrum and potent antiviral activity, with nanomolar-level activity against all genotypes (gt1a-gt6) (IC₅₀ IC₅₀ = 0.032 nM) and D168Y (IC₅₀ = 0.057 nM) . MK-2748 can be used in the research of HCV infection[1].

[1193902-95-2]

C42H56N6O10S

836.99

O=C([C@H](C[C@](OC(N1CCCCC[C@@]2([H])[C@](CCC2)([H])O3)=NC4=CC(OC)=CC=C4C1=O)([H])C5)N5C([C@H](C6CCCC6)NC3=O)=O)N[C@]7([C@H](C=C)C7)C(NS(=O)(C8(CC8)C)=O)=O

HCV; HCV Protease

Room temperature