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MK-4101 [CAS 935273-79-3]

MK-4101 [CAS 935273-79-3]

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QM-0079046-01

£51.91 GBP
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Product Details

  • Description

    MK-4101 is a Smoothened (SMO) antagonist (IC50 of 1.1 μM for 293 cells) and also a potent inhibitor of the hedgehog pathway (IC50 of 1.5 μM for mouse cells; IC50 of 1 μM for KYSE180 oesophageal cancer cells) . MK-4101 has robust antitumor activity that inhibits tumor cell proliferation and induces extensive apoptosis[1].

  • CAS Number

    [935273-79-3]

  • Molecular Formula

    C24H24F5N5O

  • Molecular Weight

    493.47

  • Smiles

    FC(C1=CC=CC=C1C2=NN=C(C34CCC(C5=NOC(C6CC(F)(F)C6)=N5)(CC4)CC3)N2C)(F)F

  • Target

    Apoptosis; Hedgehog; Smo

  • Purity

    99.16

  • Solubility

    DMSO : ≥ 50 mg/mL

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
2 mgQM-0079046-01
2 mgQM-0079046-01
£51.91/ea		 £0.00
£51.91/ea £0.00
5 mgQM-0079046-02
5 mgQM-0079046-02
£67.44/ea		 £0.00
£67.44/ea £0.00
10 mM - 1 mLQM-0079046-03
10 mM - 1 mLQM-0079046-03
£70.54/ea		 £0.00
£70.54/ea £0.00
10 mgQM-0079046-04
10 mgQM-0079046-04
£94.75/ea		 £0.00
£94.75/ea £0.00
25 mgQM-0079046-05
25 mgQM-0079046-05
£140.88/ea		 £0.00
£140.88/ea £0.00
50 mgQM-0079046-06
50 mgQM-0079046-06
£250.47/ea		 £0.00
£250.47/ea £0.00
100 mgQM-0079046-07
100 mgQM-0079046-07
£376.83/ea		 £0.00
£376.83/ea £0.00
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MK-4101 [CAS 935273-79-3]

MK-4101 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.