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SKU:QM-0142336-01
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MK2-IN-1 (compound 1) is a potent and selecitve MAPKAPK2 (MK2) inhibitor with an IC50 of 0.11 uM for MK2 and an EC50 of 0.35 uM for pHSP27. MK2-IN-1 impaires the phosphorylation level of serine residues in the Tfcp2l1 protein[1][2].
[1314118-92-7]
C27H25ClN4O2
472.97
O=C(C1=CC=C(C2=CC=C(Cl)C=C2)O1)N(C3=CC=C(N4CCNCC4)C=C3)CC5=NC=CC=C5
HSP; MAPKAPK2 (MK2)
99.04
10 mM in DMSO
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
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MK2-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.