MKLP2-IN-1 [CAS 2929345-46-8]

MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 with good oral bioavailability. MKLP2-IN-1 inhibits the microtubule-stimulated ATPase activity of recombinant MKLP2 in vitro and suppresses tumor growth in a mouse Calu-6 lung cancer model[1].

[2929345-46-8]

C23H19BrFN3O2

468.32

FC1=C(C)C=CC(CN2C(CC(C3=NN=C(C4CC4)O3)=C(Br)C5=CC=CC=C52)=O)=C1

Kinesin

Room temperature