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ML210-ansaFc
ML210-ansaFc
SKU:QM-0013299
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Product Details
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Description
ML210-ansaFc (Compound III-13) is a covalent GPX4 inhibitor with a [3]-ferrocenophane group (IC50 of 3.4 μM) . ML210-ansaFc potently induces ferroptosis by increasing the level of ROSand promoting lipid peroxidation (LPO) in cancers cells. ML210-ansaFc has an anticancer activity and suppresses tumor growth in tumor 3D spheroids. ML210-ansaFc can be used for cancer therapy resistance research[1].
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Molecular Formula
C23H23FeN3OS
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Molecular Weight
445.36
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Smiles
O=C(C1=CSC(C#C)=N1)N2CCN(CC2)C(CCc3cccc3)c4cccc4.[][Fe][]
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Target
Ferroptosis; Glutathione Peroxidase; Reactive Oxygen Species (ROS)
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Isoform
GPX4
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Shipping Conditions
Room temperature
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ML210-ansaFc
ML210-ansaFc is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.