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ML334 [CAS 1432500-66-7]

ML334 [CAS 1432500-66-7]

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SKU:QM-0136795-01

£238.32 GBP
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  • Description

    ML334 is a potent, cell permeable activator of NRF2 by inhibition of Keap1-NRF2 protein-protein interaction. ML334 binds to Keap1 Kelch domain with a Kd of 1 μM. ML334 stimulates NRF2 expression and nuclear translocation and induces antioxidant response elements (ARE) activity[1][2].

  • CAS Number

    [1432500-66-7]

  • Molecular Formula

    C26H26N2O5

  • Molecular Weight

    446.5

  • Smiles

    O=C(C1=CC=CC=C1C2=O)N2C[C@@H]3C4=CC=CC=C4CCN3C([C@H]5[C@H](CCCC5)C(O)=O)=O

  • Target

    Keap1-Nrf2; Quinone Reductase

  • Concentration

    10mM

  • Purity

    99.76

  • Solubility

    DMSO : 44.65 mg/mL (ultrasonic) |Ethanol : 44.65 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, stored under nitrogen)

  • Shipping Conditions

    Room Temperature

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5 mgQM-0136795-01
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10 mM - 1 mLQM-0136795-02
10 mM - 1 mLQM-0136795-02
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10 mgQM-0136795-03
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25 mgQM-0136795-04
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50 mgQM-0136795-05
50 mgQM-0136795-05
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100 mgQM-0136795-06
100 mgQM-0136795-06
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ML334 [CAS 1432500-66-7]

ML334 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.