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ML380 [CAS 1627138-52-6]

ML380 [CAS 1627138-52-6]

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QM-0075254-01

£124.00 GBP
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Product Details

  • Description

    ML380 is a potent, subtype-selective, and brain-penetrant positive allosteric modulator (PAM) of M5 mAChR, with EC50s of 190 and 610 nM for human and rat M5, respectively. ML380 exhibits moderate selectivity versus the M1 and M3 mAChR subtypes. ML380 could increase the affinity of ACh for the M5 mAChR[1][2][3].

  • CAS Number

    [1627138-52-6]

  • Molecular Formula

    C23H25F3N4O3S

  • Molecular Weight

    494.53

  • Smiles

    O=C(C1CCN(S(=O)(C2=CC3=C(NN=C3)C=C2)=O)CC1)N(CC)CC4=CC=CC=C4C(F)(F)F

  • Target

    MAChR

  • Isoform

    MAChR1; mAChR3; mAChR5

  • Concentration

    10mM

  • Purity

    99.87

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
5 mgQM-0075254-01
5 mgQM-0075254-01
£124.00/ea		 £0.00
£124.00/ea £0.00
10 mM - 1 mLQM-0075254-02
10 mM - 1 mLQM-0075254-02
£134.13/ea		 £0.00
£134.13/ea £0.00
10 mgQM-0075254-03
10 mgQM-0075254-03
£238.32/ea		 £0.00
£238.32/ea £0.00
25 mgQM-0075254-04
25 mgQM-0075254-04
£363.47/ea		 £0.00
£363.47/ea £0.00
50 mgQM-0075254-05
50 mgQM-0075254-05
£614.98/ea		 £0.00
£614.98/ea £0.00
100 mgQM-0075254-06
100 mgQM-0075254-06
£991.63/ea		 £0.00
£991.63/ea £0.00
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ML380 [CAS 1627138-52-6]

ML380 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.